Long-term effectiveness of first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in Ghana.
Identifieur interne : 000466 ( Main/Exploration ); précédent : 000465; suivant : 000467Long-term effectiveness of first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-based antiretroviral therapy in Ghana.
Auteurs : Fred S. Sarfo [Ghana] ; Maame Anima Sarfo ; Adetayo Kasim ; Richard Phillips ; Mark Booth ; David ChadwickSource :
- The Journal of antimicrobial chemotherapy [ 1460-2091 ] ; 2014.
Descripteurs français
- KwdFr :
- Abstention thérapeutique, Adulte, Adulte d'âge moyen, Analyse de survie, Antirétroviraux (pharmacologie), Antirétroviraux (usage thérapeutique), Benzoxazines (effets indésirables), Benzoxazines (pharmacologie), Benzoxazines (usage thérapeutique), Charge virale, Femelle, Ghana, Humains, Infections à VIH (traitement médicamenteux), Inhibiteurs de la transcriptase inverse (effets indésirables), Inhibiteurs de la transcriptase inverse (pharmacologie), Inhibiteurs de la transcriptase inverse (usage thérapeutique), Mâle, Numération des lymphocytes CD4, Névirapine (effets indésirables), Névirapine (pharmacologie), Névirapine (usage thérapeutique), Résultat thérapeutique, Thérapie antirétrovirale hautement active (), Études rétrospectives.
- MESH :
- effets indésirables : Benzoxazines, Inhibiteurs de la transcriptase inverse, Névirapine.
- pharmacologie : Antirétroviraux, Benzoxazines, Inhibiteurs de la transcriptase inverse, Névirapine.
- traitement médicamenteux : Infections à VIH.
- usage thérapeutique : Antirétroviraux, Benzoxazines, Inhibiteurs de la transcriptase inverse, Névirapine.
- Abstention thérapeutique, Adulte, Adulte d'âge moyen, Analyse de survie, Charge virale, Femelle, Ghana, Humains, Mâle, Numération des lymphocytes CD4, Résultat thérapeutique, Thérapie antirétrovirale hautement active, Études rétrospectives.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- Adult, Anti-Retroviral Agents (pharmacology), Anti-Retroviral Agents (therapeutic use), Antiretroviral Therapy, Highly Active (methods), Benzoxazines (adverse effects), Benzoxazines (pharmacology), Benzoxazines (therapeutic use), CD4 Lymphocyte Count, Female, Ghana, HIV Infections (drug therapy), Humans, Male, Middle Aged, Nevirapine (adverse effects), Nevirapine (pharmacology), Nevirapine (therapeutic use), Retrospective Studies, Reverse Transcriptase Inhibitors (adverse effects), Reverse Transcriptase Inhibitors (pharmacology), Reverse Transcriptase Inhibitors (therapeutic use), Survival Analysis, Treatment Outcome, Viral Load, Withholding Treatment.
- MESH :
- chemical , adverse effects : Benzoxazines, Nevirapine, Reverse Transcriptase Inhibitors.
- chemical , pharmacology : Anti-Retroviral Agents, Benzoxazines, Nevirapine, Reverse Transcriptase Inhibitors.
- chemical , therapeutic use : Anti-Retroviral Agents, Benzoxazines, Nevirapine, Reverse Transcriptase Inhibitors.
- geographic : Ghana.
- drug therapy : HIV Infections.
- methods : Antiretroviral Therapy, Highly Active.
- Adult, CD4 Lymphocyte Count, Female, Humans, Male, Middle Aged, Retrospective Studies, Survival Analysis, Treatment Outcome, Viral Load, Withholding Treatment.
Abstract
Information on the long-term effectiveness and tolerability of efavirenz- or nevirapine-based antiretroviral therapy (ART) in Africa is lacking. The primary objective of this retrospective observational study was to compare the long-term clinical and immunological outcomes of efavirenz- versus nevirapine-based first-line ART in a large government clinic in Ghana.
DOI: 10.1093/jac/dkt336
PubMed: 24003181
Affiliations:
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Le document en format XML
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<term>Reverse Transcriptase Inhibitors (pharmacology)</term>
<term>Reverse Transcriptase Inhibitors (therapeutic use)</term>
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<term>Withholding Treatment</term>
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<term>Humans</term>
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<term>Middle Aged</term>
<term>Retrospective Studies</term>
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<term>Treatment Outcome</term>
<term>Viral Load</term>
<term>Withholding Treatment</term>
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<term>Analyse de survie</term>
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<front><div type="abstract" xml:lang="en">Information on the long-term effectiveness and tolerability of efavirenz- or nevirapine-based antiretroviral therapy (ART) in Africa is lacking. The primary objective of this retrospective observational study was to compare the long-term clinical and immunological outcomes of efavirenz- versus nevirapine-based first-line ART in a large government clinic in Ghana.</div>
</front>
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<name sortKey="Chadwick, David" sort="Chadwick, David" uniqKey="Chadwick D" first="David" last="Chadwick">David Chadwick</name>
<name sortKey="Kasim, Adetayo" sort="Kasim, Adetayo" uniqKey="Kasim A" first="Adetayo" last="Kasim">Adetayo Kasim</name>
<name sortKey="Phillips, Richard" sort="Phillips, Richard" uniqKey="Phillips R" first="Richard" last="Phillips">Richard Phillips</name>
<name sortKey="Sarfo, Maame Anima" sort="Sarfo, Maame Anima" uniqKey="Sarfo M" first="Maame Anima" last="Sarfo">Maame Anima Sarfo</name>
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<country name="Ghana"><noRegion><name sortKey="Sarfo, Fred S" sort="Sarfo, Fred S" uniqKey="Sarfo F" first="Fred S" last="Sarfo">Fred S. Sarfo</name>
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